The deaths about 4:10 a.m. were believed to be a suicide and a homicide, police said in a media notification.
At 4:11 a.m., the woman and man were driving east on the Chicago Skyway near 88th Street when the woman ran from the vehicle, police said.
A shooting that left two people dead and shut down eastbound lanes of the Chicago Skyway during morning rush hour was an apparent murder-suicide, authorities said.
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The 30-year-old man got out of the still-moving vehicle and fired shots at the woman, striking her multiple times, police said. While the auto was still moving, the man allegedly jumped out and started shooting at the woman. Then police who were stationed near the gate approached the man, who shot himself.
Police said both victims were pronounced dead at the scene. Their identities have not been released. An Uber decal was visible on the rear window.
The Illinois Department of Transportation closed the eastbound lanes of Interstate 90 east of the Dan Ryan Expressway for much of the morning because of the police activity. The closure was not expected to be over until about 11 a.m., according to official IDOT traffic information. "I was surprised to hear about it. Normally, you hear of incidents, but you don't really hear about somebody being killed on the expressway", said Derek Bobo, a Skyway driver.